IgA nephropathy, also known as Berger's disease, is a kidney disease that occurs when a protein called immunoglobulin A (IgA) builds up in the kidneys. This buildup causes inflammation and damage to the tiny blood vessels in the kidneys called glomeruli.  

How it happens

• IgA buildup: The immune system produces IgA to fight off infections. In IgA nephropathy, IgA accumulates in the kidneys.  
• Inflammation: The buildup of IgA triggers inflammation, damaging the glomeruli.  
• Kidney damage: Over time, the damaged glomeruli can't filter waste and excess fluid from the blood effectively.  

Symptoms

Symptoms can vary widely and may include:

• Blood in urine  
• Foamy or bubbly urine (indicating protein in the urine)
• Swelling in the legs, ankles, or face  
• Fatigue  
• High blood pressure  

It's important to note that many people with IgA nephropathy have no symptoms.  

Treatment

There's currently no cure for IgA nephropathy, but treatments can help manage symptoms and slow the progression of kidney damage. These may include:  

• Blood pressure control
• Medications to reduce inflammation  
• Dietary changes  
• Dialysis or kidney transplant in severe cases  

If you suspect you may have IgA nephropathy, it's crucial to consult with a healthcare provider for diagnosis and appropriate treatment.

Would you like to know more about the causes, risk factors, or complications of IgA nephropathy?