Update March 28, 2019

 

It is caused by the Human Immunodeficiency Virus (HIV).

HIV belongs to the family Retroviridae which contains 2 copies of a single stranded RNA, with a genome packed with several enzymes.

Virus (HIV) attacks the CD4+ T lymphocytes.

HIV binds to CD4+ cells and becomes internalized.

The virus replicates itself by generating a DNA
copy by Reverse transcriptase.

Viral DNA becomes incorporated into the
host DNa, enabling further replication.

HIV virus leads an inability of the immune system of the host to fight off opportunistic disease.

 

 

 

Content 6

USMLE Reviewer

(By Subscription)