Update September 17, 2018

 

 

A 16-year-old girl presents to her family physician with concerns because she has never had a menstrual period. On physical examination, she has Tanner stage 1 breast development with normal axillary and pubic hair development. Her blood pressure is significantly higher in her arms than in her legs. A pelvic examination is unremarkable. Her parents are both phenotypically normal, and she has no brothers or sisters with any type of hereditary condition. What is the most likely diagnosis?

The correct answer is A.

Turner syndrome is a common cause of primary amenorrhea. It is associated with coarctation of the aorta, a webbed neck, short stature, and wide-spaced nipples.