Update August 22, 2018

  • This condition includes a spectrum of rare and chronic genetic, neuromuscular disorders with autosomal dominant inheritance that cause recurrent, progressive, and debilitating episodes of extreme muscle weakness and temporary paralysis that may negatively impact patients’ daily lives.7-11
  • Primary periodic paralysis is usually inherited from a parent and may affect multiple individuals within a family.12



  • Primary periodic paralysis (PPP) is very rare, affecting ~4,000 to 5,000 diagnosed individuals in the US.1
  • Although there are related variants, the most common forms are hyperkalemic and hypokalemic periodic paralysis.2-6

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