Treatment centers on the use of anticholinesterase drugs and immunosuppressants, including corticosteroids, which decrease the rate of anti-ACh receptor antibody production.

In some patients, thymectomy is effective.

Comment: Myasthenia gravis often affects the extraocular and bulbar musculature. Myasthenia gravis should not be confused with the myasthenic syndrome (Lambert–Eaton syndrome), an autoimmune disease seen in the context of systemic neoplasms (especially those affecting the lung and breast). In the myasthenic syndrome, abnormal antibodies directed against presynaptic Ca2+ channels interfere with the release of ACh from the presynaptic ending at the neuromuscular junction.