Embryonic development, fetal maturation, and perinatal changes

hypothalamus, posterior and anterior pituitary gland

thyroid gland

parathyroid gland

adrenal cortex, adrenal medulla

pancreatic islets

ovary and testis

adipose tissue

Organ structure and function

hypothalamus,

posterior and anterior pituitary gland

thyroid gland

parathyroid gland

adrenal cortex,

adrenal medulla

pancreatic islets

ovary and testis

adipose tissue

Cell/tissue/structure and function, including hormone synthesis, secretion, action, metabolism

peptide hormones

steroid hormones, including vitamin D thyroid hormones

catecholamine hormones renin-angiotensin system

Repair, regeneration, and changes associated with stage of life

Abnormal Processes: Health and Health Maintenance, Screening, Diagnosis, Management, Risks, Prognosis

(Step 2 & 3 Emphasis)

Diabetes mellitus and other disorders of the endocrine pancreas

diabetes mellitus:

diabetes mellitus, type 1;

diabetes mellitus, type 1.5;

diabetes mellitus, type 2;

diabetes mellitus, acute complications:

hyperosmolar coma,

hypoglycemic shock,

ketoacidosis, including cerebral edema, associated electrolyte abnormalities;

diabetes mellitus, chronic complications:

gastrointestinal/gastroparesis,

neurologic/neuropathy,

ophthalmologic/retinopathy,

peripheral vascular

renal/nephropathy,

metabolic syndrome

hypoglycemia and islet cell disorders:

hypoglycemia (secondary to insulinoma, surreptitious insulin use, sepsis, liver failure);

hyperglycemia (secondary to glucagonoma);

hyperinsulinism;

islet cell tumors/insulinoma/somatostatinoma;

pancreatic neuroendocrine tumors

Thyroid disorders:

cyst, nodule;

euthyroid sick syndrome;

goiter (euthyroid-normal thyroid function with goiter);

hypothyroidism;

hyperthyroidism, including thyrotoxicosis and thyroid storm;

thyroiditis, including Hashimoto;

Graves disease;

neoplasms (benign cysts and nodules, thyroid cancer including papillary, follicular, medullary, and anaplastic);

thyroid deficiency from pituitary disorder;

infertility due to thyroid disease;

secondary hypothyroidism and hyperthyroidism

Parathyroid disorders:

hyperparathyroidism;

hypoparathyroidism;

metabolic bone disease

Adrenal disorders:

corticoadrenal insufficiency (Addison disease);

adrenal insufficiency, secondary;

hypocortisolism;

Cushing disease, Cushing syndrome;

hyperaldosteronism;

neoplasms, benign and malignant (adrenal neuroblastoma, pheochromocytoma, adrenal carcinoma, adrenal adenoma, aldosteronoma, adrenal incidentaloma);

delayed and precocious puberty;

hypertensive endocrine disease (pheochromocytoma; hypercortisolism; aldosteronoma)

Pituitary disorders:

acromegaly/gigantism;

diabetes insipidus;

galactorrhea not associated with childbirth;

panhypopituitarism from any cause;

pituitary apoplexy (eg, Sheehan syndrome);

growth hormone deficiency;

short stature;

SIADH (inappropriate secretion of ADH [vasopressin]);

neoplasm, benign and malignant (pituitary adenomas, craniopharyngioma, metastatic disease);

prolactinoma and hyperprolactinemia, including infertility due to these disorders;

hypogonadism, primary and secondary

female hypogonadism

Hypothalamic endocrine disorders

damage resulting from malnutrition, including anorexia and bulimia eating disorders, genetic disorders, radiation, surgery, head trauma, lesion,[1] tumour or other physical injury to the hypothalamus. 

Multiple endocrine neoplasia (MEN1, MEN2)

Congenital disorders:

disorders of sexual differentiation;

congenital adrenal hyperplasia;

androgen insensitivity/resistance syndrome;

congenital hypothyroidism

Adverse effects of drugs on the endocrine system:

Thyroid and Parathyroid

drug, medicinal, and biologic substance effects;

exogenous steroid suppression of adrenal glands, anabolic steroids

Adverse effects of medicinal drugs on the endocrine system